2012Natural Product ResearchDOI: 10.1080/14786419.2012.665916

<i>In vitro</i>biological activities of the essential oil from the ‘resurrection plant’<i>Myrothamnus moschatus</i>(Baillon) Niedenzu endemic to Madagascar

Publication Authors

Marcello Nicoletti, Filippo Maggi, Fabrizio Papa, Sauro Vittori, Luana Quassinti, Massimo Bramucci, Giulio Lupidi, Dezemona Petrelli, Luca A. Vitali, Ermenegilde Ralaibia, Philippe Rasoanaivo

Faculty Researcher

1 researcher

Boniface Erménégilde RALAIBIA

Maitre de Conférences

Abstract

Abstract & synthèse du document

The essential oil of the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar, where it is used in traditional medicine, was investigated for the first time for some biological activities. GC-FID and GC-MS analyses revealed trans-pinocarveol (35.6%), pinocarvone (20.0%), β-selinene (8.5%) and perillyl acetate (6.0%) as the major essential oil constituents. The oil strongly inhibited MDA-MB 231 (human breast adenocarcinoma) cells, with an IC(50) of 15 µg mL(-1), and the growth of Candida albicans, with an inhibition diameter of 18 mm, while its antioxidant activity, measured by DPPH and ABTS assay, proved to be negligible.

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